Bs-ADC
Bs-ADC:
One leading product BTA-010 is in the mid-late preclinical stage. BTA-032 and BTA-020 are in the early preclinical stage. IND application of BTA-010 is expected in Q3/ 2026.
- Monovalent bispecific antibody-drug conjugation targeting EGFR and cMet with established cysteine-based conjugation
- Highly homogeneous conjugated product (DAR=4)
- Optimized activities on EGFR and cMET to promote selectivity and cytotoxicity
- High stability with drug conjugation
- Afford opportunities for combinationwith TKI andcheckpoint blockers