Bs-ADC

Bs-ADC:

One leading product BTA-010 is in the mid-late preclinical stage of development; BTA-032 and BTA-020 are in the early preclinical stage of development. IND application of BTA-010 is expected in Q1/2026

BTA-010
  • Monovalent bispecific antibody-drug conjugation targeting EGFR and cMet with novel design of cysteine-based conjugation
  • Highly homogeneous conjugated product (DAR=4)
  • Optimized activities on EGFR and cMET to promote selectivity and cytotoxicity
  • High stability with drug conjugation; melting temperature similar to IgG molecules
  • Afford opportunities for combinationwith TKI andcheckpoint blockers
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